Acute Kidney Injury: Pathophysiology and Clinical Management of a Case Study

Overview

This paper examines a case study of Sally Jones, a 56-year-old female presenting with acute kidney injury and kidney stones. The paper uses evidence-based information to analyze the pathophysiology of AKI, kidney stone formation, associated risk factors, and clinical diagnostic findings to provide comprehensive understanding of the concurrent conditions.

What this case study covers

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Acute Kidney Injury

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Acute Kidney Injury

Kidney stones are hard deposits of acid salts and minerals that form inside the kidneys and may obstruct the kidneys' connection to the bladder. Kidney stones do not cause permanent damage if they are detected quickly, although surgery may be necessary if lodged in the urinary tract. On the other hand, Acute Kidney Injury (AKI), also referred to as acute renal failure (ARF), is an abrupt deterioration in renal filtration capacity (usually over a short period of two days or less) involving both structural damage and loss of function. AKI is often reversible if determined and treated quickly: patients regain full function of the kidneys after treatment, although delays in treatment may result in lasting damage, including chronic kidney disease or kidney failure. This essay will use evidence-based information to examine the case study of Sally Jones, a 56-year-old female who presents the symptoms of both AKI and kidney stones.

Pathophysiology

An interview of the patient revealed that she was experiencing the following symptoms: worsening right-sided flank, nausea, lack of appetite, infrequent urination, and night fever. Physical examination indicated BP 124/87, HR 108 bpm, Temp 37.9OCelsius, and Resp 20 bpm. The patient passed 150mls of haematuria/cloudy urine since admission 5 hours ago but is alert and oriented. Diagnostic studies were as follows: urinalysis – positive for blood, nitrates, and proteins; U&Es – Na 139mmol/l, K 4.

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