Western Governors University

D312: Anatomy and Physiology I with Lab

A study guide to WGU's D312, the self-paced course on body organization and the integumentary, skeletal, muscular, nervous and endocrine systems.

Updated October 2026 · 5 min read

D312 Anatomy and Physiology I is the Western Governors University course on how the body is organized and how five systems work: integumentary, skeletal, muscular, nervous and endocrine.

WGU's program guide for the B.S. Nursing (RN to BSN) describes it as a six-section, four-competency-unit course using lab activities, simulated dissections, textbook material, models and diagrams. It is self-paced, and WGU estimates 40 to 60 hours for students with no prior knowledge.

The volume of new vocabulary is the first hurdle. The second is moving beyond naming parts to explaining how a structure's shape suits its function and how systems influence each other.

Course at a Glance

ItemDetails
UniversityWestern Governors University (WGU)
Course codeD312
LevelUndergraduate
Competency units4
FormatSelf-paced, six sections, lab activities and simulated dissections
Next courseAnatomy and Physiology II with Lab

What D312 Covers

Area (from WGU's competencies)Key ideas to master
Body organization and terminologyLevels of organization, directional terms, planes, body regions and cavities
Integumentary systemSkin layers, glands, thermoregulation, protection and healing
Skeletal systemBone tissue, remodelling, calcium balance, joints
Muscular systemMuscle types, sliding filament mechanism, neuromuscular junction
Nervous system and sensesNeurons, action potentials, synapses, brain and spinal cord, special senses
Endocrine systemHormones, feedback loops, glands and their targets

Key Concepts Explained

Directional Terms and Planes

Anatomy uses a fixed reference, the anatomical position, so descriptions are unambiguous. Superior and inferior, anterior and posterior, medial and lateral, proximal and distal appear throughout every later topic.

Example: "The wrist is proximal to the fingers and distal to the elbow" makes sense only if you picture the limb's attachment point. Practice by describing the position of structures on your own body until the terms become automatic.

Negative Feedback

Most body systems keep variables stable through negative feedback: a change triggers a response that reverses it. The endocrine system relies on this constantly.

Example: When blood calcium falls, the parathyroid glands release parathyroid hormone, which raises calcium by releasing it from bone and increasing reabsorption by the kidneys. As calcium returns to normal, hormone release falls. This one loop links the endocrine, skeletal and urinary systems.

Action Potentials

Nerve signals are rapid changes in membrane voltage: sodium rushes in (depolarisation), potassium flows out (repolarisation), and pumps restore the resting state. Muscle contraction starts with the same kind of signal at the neuromuscular junction.

Coursework and Assessment

WGU describes the course as built around lab activities, simulated dissections, models and diagrams, with the aim of demonstrating proficiency in the competencies covered in the final assessment. Check your course page for the assessment format and any lab submissions.

ActivityWhat it buildsHow to use it
Simulated dissectionsSpatial understandingName each structure and say what it does
Diagrams and modelsRecognitionRedraw from memory, then check
Lab activitiesApplying conceptsPredict the result before you see it
Practice questionsExam readinessAnalyze why wrong options are wrong

How the Five Systems Work Together

WGU's competencies repeatedly mention connections to complex systems in the body, so expect questions that cross system boundaries. The five systems in D312 are tightly linked.

Example: On a hot day, temperature sensors signal the hypothalamus (nervous system), which triggers sweating and widening of skin blood vessels (integumentary system). Resting muscles produce less heat (muscular system), and hormones help regulate metabolism over longer periods (endocrine system). One scenario touches four systems.

When revising, take each system and write two sentences on how it depends on another. Movement needs bones, muscles and nerves; bone health depends on hormones; skin helps produce vitamin D, which supports calcium absorption for bone.

Where Students Get Stuck

Study Tips for D312

How We Help with D312

Tell us which sections, systems or practice questions are difficult. A tutor with a health science background can explain concepts step by step, produce revision summaries and talk you through lab and dissection activities.

GradeEssays is independent of Western Governors University. We provide tutoring and study materials only; we never take assessments or access your course, and we do not promise results. Revisions within the scope of your original request are free.

Learn a&P I in a Way That Sticks

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Frequently Asked Questions

How long does D312 take?

WGU estimates 40 to 60 hours of course content for students with no prior knowledge. The course is self-paced, so your time will vary.

Which body systems are in D312?

The integumentary, skeletal, muscular, nervous and endocrine systems, plus body organization and terminology.

Is there a real lab?

WGU describes laboratory activities, simulated dissections, models and diagrams as part of the course.

What comes after D312?

Anatomy and Physiology II with Lab (D313), which covers the cardiovascular, respiratory, digestive, urinary, reproductive and lymphatic systems.

What is the hardest part of A&P I?

Many students find the nervous and endocrine systems hardest because they involve sequences and feedback loops rather than simple structures.

Can you take my D312 assessment?

No. We offer tutoring and study notes only; assessments must be completed by you.