University of Maryland Global Campus

BIOL 220: Human Genetics

A study guide to UMGC's BIOL 220, an introduction to how genes shape inherited traits, genetic variation and genetic disorders in people.

Updated October 2026 · 5 min read

BIOL 220 is UMGC's three-credit introduction to the role of genes in the inheritance of traits and of genetic diseases and disorders in humans.

The University of Maryland Global Campus describes the course as examining how genetic factors influence physical characteristics and behavioral traits. It covers Mendelian and non-Mendelian inheritance, human genetic variation and the mechanisms of genetic disease.

The course is human-focused, so examples come from real conditions and families. Students usually find the problem solving (pedigrees, probabilities) the hardest part, along with explaining why a mutation leads to a particular disorder.

Course at a Glance

ItemDetails
UniversityUniversity of Maryland Global Campus (UMGC)
Course codeBIOL 220
Credits3
LevelUndergraduate
Credit noteCredit for only one of BIOL 220, BIOL 222 or BSCI 222
Related labBIOL 224, Genetics Laboratory (1 credit)

What BIOL 220 Covers

TopicIn plain language
DNA, genes and chromosomesWhere genetic information sits and how it is copied and passed on
Mendelian inheritanceDominant and recessive patterns, autosomal and X-linked traits
Non-Mendelian inheritanceIncomplete dominance, codominance, multiple alleles, polygenic and mitochondrial traits
Human genetic variationHow and why people differ genetically
Genetic diseaseMutations, chromosome abnormalities and how they cause disorders
Genes and behaviorHow genes and environment together influence traits

Key Concepts Explained

Autosomal Recessive Inheritance

A recessive disorder appears only when a person inherits two copies of the variant allele. Carriers have one copy and are usually unaffected.

Example: Two carriers of cystic fibrosis (Aa x Aa) have, for each child, a 1 in 4 chance of an affected child (aa), a 1 in 2 chance of a carrier (Aa) and a 1 in 4 chance of a non-carrier (AA). Each pregnancy is independent.

X-Linked Recessive Inheritance

Males have one X chromosome, so a single recessive X-linked allele is enough to cause the condition. This is why conditions such as red-green color blindness are more common in males.

Example: A carrier mother (XAXa) and an unaffected father (XAY): each son has a 1 in 2 chance of being affected; each daughter has a 1 in 2 chance of being a carrier.

Multifactorial Traits

Height, skin color and many common diseases depend on several genes plus environment. They do not follow simple ratios, and good answers say so rather than forcing a Punnett square.

Typical Assignments and How to Approach Them

Assignment typeWhat it testsHow to approach it
Inheritance problemsProbability and inheritance patternsWrite genotypes first, then the cross, then the answer
Pedigree analysisIdentifying the mode of inheritanceTest each pattern against the chart and rule out the rest
Genetic disorder paperExplaining cause, inheritance and impactGene, mutation, mechanism, inheritance, diagnosis, ethics

Genetic Testing and Ethics

Human genetics raises questions that go beyond the science, and short essays often ask you to consider them. Common themes include carrier screening, prenatal testing, direct-to-consumer DNA tests and the privacy of genetic data.

A strong answer first explains what a test can and cannot show. Many tests report risk rather than certainty, especially for multifactorial conditions. It then considers who benefits, who could be harmed and what safeguards exist.

Example: A positive result for a BRCA1 variant raises lifetime breast and ovarian cancer risk but does not mean cancer will develop. Discuss what the result means medically, then the choices and family implications it creates.

Where BIOL 220 Fits

BIOL 220 is a good choice if you want human-centered genetics without the BIOL 105 prerequisite that BIOL 222 carries. Because UMGC allows credit for only one of BIOL 220, BIOL 222 or BSCI 222, check your degree plan before enrolling: some science programs may expect the broader course.

Where Students Get Stuck

Study Tips for BIOL 220

How We Help with BIOL 220

Send the assignment, problem set or paper prompt, the rubric and any feedback. A writer with a genetics background can work through problems step by step, explain the reasoning behind a pedigree, or review your paper on a genetic disorder.

GradeEssays is independent of the University of Maryland Global Campus. Our solutions and papers are study aids: use them to learn the method, then complete and submit your own work under UMGC's academic integrity policy. We write from scratch and offer free revisions within the scope of your original request.

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Frequently Asked Questions

Can I take both BIOL 220 and BIOL 222?

No. UMGC allows credit for only one of BIOL 220, BIOL 222 or BSCI 222.

How is BIOL 220 different from BIOL 222?

BIOL 220 focuses on human inheritance and genetic disease. BIOL 222 is a broader study of heredity and gene expression from molecules to populations and requires BIOL 105.

Is there maths in BIOL 220?

Basic probability for crosses and pedigrees. The rules are simple once practiced.

Is there a lab for genetics at UMGC?

Yes, BIOL 224 Genetics Laboratory, which takes BIOL 220 or BIOL 222 as a prerequisite or corequisite.

Which disorders make good paper topics?

Well-documented single-gene conditions such as cystic fibrosis, sickle cell disease or Huntington's disease have strong literature. Follow your prompt.

Can you check my pedigree answers?

Yes. Send your work and we explain any errors and the correct reasoning.