1. DNA contains our hereditary information and that genetic

1. DNA contains our hereditary information and that genetic information flows in one direction (known as The Central Dogma).

a. What three major macromolecules are involved in gene expression?

b. What two processes are involved in gene expression?

2. Explore DNA

a. DNA naturally exists as a _________________.

b. However, if you laid DNA out flat, it would look like a ________.

c. In eukaryotic cells, DNA is found in the _____________.

d. However, ribosomes are in the __________.

3. Click on the link to Leber Congenital Amaurosis, watch the video, and read about potential gene therapy for this autosomal recessive disorder.

1. What type of microbe is being used to deliver nucleic acids into specific cells using gene therapy?
2. What organ is being affected by Leber Congenital Amaurosis?
3. What gene are scientists targeting during gene therapy treatment for Leber Congenital Amaurosis?
4. What is the goal of gene therapy for Leber Congenital Amaurosis?